Progesterone Cream

 Natpro 60 gm Tube:

2000 mg progesterone per 60gm tube

166 mg progesterone per 5ml = 1tsp

1 ml contains 33.3 mg progesterone

Contents:
De-ionised water, Caprylic/capric triglyeride, natural progesterone 2000 mg, Cetearyl olivate, Sorbitan olivate, Populus tremuloides (Aspen bark extract), Di-alpha tocopherol (Vitamin E)

Free from animal deriatives, added fragrance, mineral oils, colorants, not tested on animals, pH balanced

Progesterone Cream: Overview & Therapeutic Benefits

Progesterone is a natural steroid hormone found in much higher concentrations in women than men. In the female body, it operates harmoniously with estrogen and other steroid hormones to regulate vital physiological functions, such as managing the menstrual cycle and preparing the uterine lining for the implantation of a fertilized egg.

Unlike synthetic alternatives, natural progesterone cream is an over-the-counter topical product used to ease peri-menopausal and menopausal symptoms, balance hormonal shifts, improve sleep quality, reduce anxiety, and support overall cellular health.

The Wide Spectrum of Natural Progesterone Applications

Because progesterone plays a foundational role in cellular, neurological, and endocrine health, natural progesterone therapy can be effective in treating a wide range of health conditions, including:

• Neurological & Psychological Health: Post-natal psychosis, traumatic brain injury (TBI), neuro-degeneration, anxiety, stress, and sleep disturbances/insomnia.
• Nerve & Muscle Function: Peripheral neuropathy and myopathy.
• Reproductive & Hormonal Disorders: Endometriosis, fibroids, Polycystic Ovary Syndrome (PCOS), peri-menopause, menopause, hot flushes, candida, and hormonal migraines.
• Pregnancy Support: Pregnancy complications, including recurring miscarriages and pre-term births.
• Men’s Health: Benign Prostatic Hyperplasia (BPH) and gynecomastia (‘man boobs’).
• Dermatological & Cellular Health: Acne and cancer support.

Key Roles of Progesterone in the Body

As a versatile precursor to other essential steroid hormones—including cortisol, testosterone, and estrogens (estriol, estradiol, and estrone)—progesterone carries out several critical functions:

• Uterine & Breast Protection: Maintains the uterine lining, prevents excess tissue buildup, and inhibits breast tissue overgrowth.
• Metabolic & Fluid Balance: Balances blood sugar, boosts metabolism, acts as a natural diuretic, and normalizes blood clotting.
• Bone & Glandular Support: Stimulates the production of new bone tissue, counters the bone-thinning effects of aging, and improves the action of thyroid hormones.
• Mood & Vitality: Reduces anxiety and depression, improves libido, and promotes natural sleep patterns.

Major Benefits of Topical Progesterone Cream

Application of progesterone cream serves as a form of natural hormone replacement therapy (HRT) to restore physiological balance:

1. Menopause Relief: Helps reduce the frequency and intensity of hot flashes and night sweats.
2. Better Sleep: Promotes a calming effect on the central nervous system, helping ease insomnia and restless sleep.
3. Mood Support: Helps take the edge off irritability, nervous tension, and mild anxiety.
4. Skin Health: Topical application shows localized improvements in skin firmness, hydration, and elasticity.

Natural Bio-identical Progesterone vs. Synthetic Progestins

A critical distinction must be made between natural bioidentical progesterone and synthetic progestins (or progestogens).

Natural Progesterone

Natural bioidentical progesterone is identical in molecular structure to the hormone produced by the human body. Because of this exact fit, the natural hormone has no toxic side effects when used properly to restore physiological balance.

Synthetic Progestins & Progestogens should be avoided:

Synthetic progestins and progestogens have an altered molecular structure. Because of this altered shape, progestins behave in the body in radically different—and potentially harmful—ways compared to progesterone itself. Consequently, synthetic progestins are potentially highly toxic and are associated with significant adverse effects

Further information:

“What is it?”

First of all its a hormone that has been around for about 500 million years. That makes it the oldest hormone.

Why is this important?

Because it shows how vital it is to the lives of a great many creatures on the planet.

It is essential to all vertebrates… fishes, reptiles, birds and mammals… including humans.

It has countless functions in both sexes and all ages… regulating blood sugar, developing intelligence, building bones, brain activity and many more.

Our bodies make it all the time.

This vital hormone plays a major role in the body. It is not exclusively a female hormone nor is it a ‘sex’ hormone. It plays no part in the secondary sexual characteristics which develop at puberty. It is the precursor to the sex hormones oestrogen and testosterone.

It is secreted primarily by the ovaries in females and the testes in men. Smaller amounts are produced by the adrenal glands, the brain and glial cells in both sexes.

There are no great quantitative differences between men and women (at least outside the luteal phase).

William Allen and George Corner first isolated ‘Progestational Steroidal Ketone’ (these are the words that fully describe the hormone and which are the source of its commonly used name) in 1934 and proposed the name because of its “progestational” activity in the pregnant female. This was an unfortunate choice of name as it has now come to be regarded as a ‘female’ sex hormone, and it’s many other roles having been largely forgotten.

It was not until 1943 that Russell Marker made progesterone from the plant steroid diosgenin. Originally he used the Mexican wild yam (dioscorea villosa) as a source plant. However, diosgenin has now been found in many other plants, including the spice fenugreek and the soya bean.

Once it was established that it could be produced like this biochemists began converting it into other hormones. These include cortisone, testosterone, estrogen and of course the unnatural ‘progestins’ or ‘progestogens’ that masquerade as the real, natural hormone.

There is much confusion in the minds of both the public and the professions between progesterone on the one hand, and the progestins or progestogens and “yam extracts” on the other.

Let me clear the confusion for you.

Progesterone is made in your body from cholesterol. Here are the essentials of the process…

• first, your body turns the cholesterol into pregnenolone
• pregnenolone is then converted to progesterone
• your body then makes a cascade of other hormones that it needs from the progesterone (these include the estrogens and testosterone amongst others)

See this document for added clarity… Steroidgenesis Pathway

This is the vital point to understand…

It’s this simple fact that helps anyone appreciate just how wide ranging the effects of a deficiency can be.

This is why progesterone therapy can be effective in treating such a wide range of health problems, from…

• • post natal psychosis, to
  • traumatic brain injury (TBI)
  • myopathy
  • peripheral neuropathy
  • pregnancy problems such as miscarriages and pre-term births
  • cancer
  • sleep
  • anxiety and stress
  • Hot Flushes
  • neuro-degeneration
  • PCOS
  • benign prostate hyperplasia
  • ‘man boobs’
  • acne
  • endometriosis

fibroids

• peri-menopause
• menopause
• miscarriage
• candida
• migraines

…and many more.

The “natural” hormone your body makes has a unique molecular structure. Here’s what it looks like…

The synthetic progestins and progestogens on the other hand have an altered molecular structure. Here’s what they look like…

Spot the difference? They may look similar to the real thing… just as ivy and spinach are both green and leafy (ivy quiche anyone?).